Dobrava virus: a mortal agent of hemorrhagic fever with renal syndrome.
نویسنده
چکیده
منابع مشابه
Isolation of Dobrava virus from Apodemus flavicollis in Greece.
Dobrava virus (DOBV) carried by Apodemus flavicollis is the causative agent of severe hemorrhagic fever with renal syndrome (HFRS). DOBV was isolated from an A. flavicollis mouse trapped in northeastern Greece. This is the third DOBV cell culture isolate in the world, clustering together with other Greek DOBV sequences from HFRS patients and rodents.
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This report describes the first investigation of clinical findings for a larger series of patients with hemorrhagic fever with renal syndrome (HFRS) who were infected with Dobrava virus. From 1985 to 1995, 38 patients with serologically confirmed HFRS were hospitalized at the regional hospital in Novo mesto in the Dolenjska region of Slovenia. On the basis of results of serological examination,...
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Sir: Hantaviruses (genus Hantavirus, family Bunyaviridae) are carried worldwide by rodents, bats and insectivores. In Europe, hemorrhagic fever with renal syndrome (HFRS) may be caused by infection with Dobrava virus (DOBV), carried by Apodemus flavicollis (yellow-necked mouse). A milder form of HFRS –nephropathia epidemica-may be caused by infection with Puumala virus (PUUV), carried by Myodes...
متن کاملCharacterization of Hemorrhagic Fever with Renal Syndrome Caused by Hantaviruses, Estonia
Thirty cases of hemorrhagic fever with renal syndrome (HFRS) due to Puumala virus (PUUV), Saaremaa virus (SAAV), and Dobrava virus infection were confirmed in Estonia. Except for the levels of serum creatinine, no remarkable differences were found in the clinical course of HFRS caused by PUUV and SAAV.
متن کاملDobrava virus RNA load in patients who have hemorrhagic fever with renal syndrome.
To asses the role of virus load in the pathogenesis of hemorrhagic fever with renal syndrome, the serum Dobrava virus RNA load in 46 patients was measured with a novel quantitative real-time reverse-transcriptase polymerase chain reaction assay and compared to the disease severity. The level of viremia, detected in 26 patients, ranged from 10(2)-10(8) copies/mL of serum. The patients with sever...
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عنوان ژورنال:
- Journal of infection in developing countries
دوره 7 10 شماره
صفحات -
تاریخ انتشار 2013